Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at full length human ERbeta receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase report... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115670 BindingDB Entry DOI: 10.7270/Q2ZK5MCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at full length human ERalpha receptor assessed as transcriptional activity incubated for 22 to 24 hrs by cell based luciferase repor... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115670 BindingDB Entry DOI: 10.7270/Q2ZK5MCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of fluormone from GST-tagged ERbeta receptor LBD (unknown origin) measured after 60 mins by TR-FRET competitive binding assay | Citation and Details Article DOI: 10.1016/j.bmc.2020.115670 BindingDB Entry DOI: 10.7270/Q2ZK5MCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >10 | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at full length human ERbeta receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell ba... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115670 BindingDB Entry DOI: 10.7270/Q2ZK5MCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >50 | n/a | n/a | n/a | n/a |
TBA | Assay Description Antagonist activity at full length human ERalpha receptor assessed as inhibition of estradiol-induced activation incubated for 22 to 24 hrs by cell b... | Citation and Details Article DOI: 10.1016/j.bmc.2020.115670 BindingDB Entry DOI: 10.7270/Q2ZK5MCF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from estrogen receptor in immature rabbit | J Med Chem 32: 1642-52 (1989) BindingDB Entry DOI: 10.7270/Q25141F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (RAT-Rattus norvegicus) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 1.68E+3 | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Displacement of [3H]-estradiol from estrogen receptor in mature rat | J Med Chem 32: 1642-52 (1989) BindingDB Entry DOI: 10.7270/Q25141F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (Homo sapiens (Human)) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 3.37E+3 | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Displacement of [3H]estradiol from estrogen receptor in squirrel monkey | J Med Chem 32: 1642-52 (1989) BindingDB Entry DOI: 10.7270/Q25141F8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor beta (RAT-Rattus norvegicus) | BDBM50187243 (17-ethinyl-3,17-estradiol | 17-ethinyl-3,17-oestra...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | >3.37E+4 | n/a | n/a | n/a | n/a |
SRI International Curated by ChEMBL | Assay Description Displacement of [3H]-estradiol from estrogen receptor in immature rat | J Med Chem 32: 1642-52 (1989) BindingDB Entry DOI: 10.7270/Q25141F8 | |||||||||||
More data for this Ligand-Target Pair |